Financial Controller (Hybrid)
Company: MPN Research Foundation
Location: Chicago
Posted on: April 1, 2026
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Job Description:
MPN Research Foundation is dedicated to funding and advancing
original research in pursuit of new treatments—and eventually a
cure—for essential thrombocythemia (ET), polycythemia vera (PV),
and myelofibrosis (MF), blood cancers that are known collectively
as myeloproliferative neoplasms (MPN). Founded in 1999, MPNRF was
the first organization in the MPN space and is the only one focused
on advancing research. From its unique position at the intersection
among three key stakeholders—patients, researchers/clinicians, and
the biopharma/biotech industry—MPNRF facilitates a collaborative
approach to research that elevates the patient voice in research
and drug development, brings disease experts together, and
accelerates the industry’s understanding of an extremely complex
group of diseases. Job Summary We are seeking a skilled and
proactive finance professional to operate as the MPN Research
Foundation Controller, leading financial operations, reporting,
compliance, and system improvements. This role offers an
opportunity to shape and strengthen the financial infrastructure of
a growing nonprofit committed to patient impact. The ideal
candidate is hands-on, detail-oriented, and thrives in a remote
small “roll-up-your-sleeves” environment. They will own the
day-to-day finance function while identifying opportunities to
improve systems and workflows. They will be personally responsible
for driving any financial operational improvements. This position
will report to the Director of Operations with a direct line to the
CEO. Primary Duties and Responsibilities Controller
Responsibilities Prepare monthly and annual financial statements
and dashboards Maintain and manage the general ledger in QuickBooks
Lead audit preparation and review Ensure compliance with state
charitable registrations and reporting Support leadership with
budgeting and financial planning Comply with all state and federal
requirements Bookkeeping & Daily Operations Triage and manage
finance-related inbox communications with service level agreements
(SLAs) Process invoices and vendor payments timely Lead daily
bookkeeping and routine transaction recording in QuickBooks Lead
all payroll, benefit contributions, and reporting coordination in
compliance with state and federal laws Match and reconcile revenue
(donations, contributions, grants, sponsorships, and program
income) in Salesforce with QuickBooks Develop & execute process
improvements as needed Operational Improvements & Tech Integration
Troubleshoot and reduce manual effort in lockbox operations (e.g.,
1:1 folder match issue) Recommend and implement
automation/integration improvements with platforms such as Fidelity
Charitable, JustGiving, etc. Improve donation and reporting
workflows within Salesforce Collaborate with staff using Monday.com
and Microsoft 365 tools Benefit plan management State registration
& unemployment tax compliance Education and Experience Requirements
5 years of finance/accounting experience, Strong knowledge of GAAP
and nonprofit or fund accounting practices Experience preparing for
and managing audits and compliance reporting Proficiency with
QuickBooks, Excel, Microsoft 365 Familiarity with Salesforce, donor
platforms, and project management tools like Monday.com Strong
organizational skills and ability to work independently and
collaboratively Worked on a small team or start-up with experience
truly owning the entire financial function Compensation & Benefits
Hybrid remote/in-person Chicago office with standard business hours
(i.e. 9:00 AM – 5:00 PM CST) Chicagoland based Unlimited time off
plus holidays Opportunity to contribute to meaningful work in a
mission-driven organization Eligible for medical, dental benefits,
and 401k match program
Keywords: MPN Research Foundation, Mount Prospect , Financial Controller (Hybrid), Accounting, Auditing , Chicago, Illinois